Description
What is YK-11?
YK-11 (Myostine) is a synthetic myostatin inhibitor often categorized as a SARM, though structurally it resembles a steroidal compound. Originally developed for its ability to stimulate muscle growth through selective activation of androgen receptors and suppression of myostatin—a protein that limits muscle development—YK-11 is considered one of the most potent compounds in the SARMs category.
How Does YK-11 Work?
YK-11 binds selectively to androgen receptors in muscle tissue while inhibiting myostatin. Myostatin prevents excessive hypertrophy, so by blocking it and enhancing follistatin expression, YK-11 may accelerate muscle growth and strength gains in research settings.
Its steroidal backbone differentiates it from other SARMs, producing a more intense anabolic response. Because of this, YK-11 is often used in short, high-impact research cycles with careful monitoring.
Chemical Properties
| Chemical Name | YK-11 |
| CAS Number | 1370003-76-1 |
| Molecular Formula | C25H34O6 |
| Molecular Weight | 430.54 g/mol |
| IUPAC Name | 17α-methyl-5α-androstano[17,16-d]pyrazolo[1′,5′:1,2]pyrimidin-3-one |
Potential Benefits of YK-11
- Extreme Muscle Growth: May trigger rapid hypertrophy via myostatin inhibition.
- Strength Increase: Performance-based studies suggest fast force output gains.
- Fat Loss Support: Enhanced lean-to-fat ratio through higher metabolic demand.
- Bone Density: May improve bone strength by increasing mineral density.
Clinical Research & Findings
While data is more limited compared to other SARMs, early research highlights YK-11’s immense anabolic potential. Reports show significantly upregulated follistatin production and suppressed myostatin expression—both markers of accelerated muscle development. Because of its potency, it is typically reserved for short, high-intensity research protocols, with attention to testosterone suppression and liver enzyme markers.
Dosage & Research Protocols
In research settings, YK-11 is commonly studied in moderate dosages:
- Muscle Mass & Strength Gains: 10–15mg per day for 6–8 weeks
- Recomp or Cutting Cycle: 5–10mg per day for 6 weeks
- Strength Focused Research: 10mg per day for 4–6 weeks
Due to its short half-life (6–10 hours), split dosing is advised to maintain stable levels. Research cycles rarely exceed 8 weeks. Post-cycle therapy (PCT) is recommended because YK-11 can suppress natural testosterone.
FAQs
Is YK-11 legal in Canada?
Yes. YK-11 is legal for research use in Canada, though it is not approved for human consumption.
Does YK-11 suppress testosterone?
Yes. Studies and anecdotal data suggest YK-11 significantly suppresses testosterone, making PCT essential.
How long is the half-life of YK-11?
Research suggests a half-life of 6–10 hours, supporting split daily dosing in research protocols.
What form does this product come in?
Available in powder and liquid form with ≥98% purity for laboratory research use only.
Disclaimer
For laboratory use only. Not for human or veterinary use.
This material is intended strictly for research purposes under controlled laboratory conditions. It is the buyer’s responsibility to ensure legal and ethical use in accordance with institutional, local, and federal guidelines. Always wear proper safety equipment and follow appropriate handling procedures.

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