Description
What is TB-500?
TB-500 is a synthetic peptide fragment of Thymosin Beta-4, a naturally occurring protein found in nearly all human and animal cells. This peptide is specifically designed around the active region of Thymosin Beta-4 responsible for healing and regenerative effects. Research into TB-500 focuses on its potential to accelerate recovery from injuries, promote angiogenesis (new blood vessel formation), and improve tissue resilience.
How Does TB-500 Work?
TB-500 is studied for its ability to regulate actin, a key protein involved in cell structure and migration. By promoting actin upregulation, TB-500 facilitates faster wound healing, new blood vessel development, and tissue regeneration. Research also suggests anti-inflammatory properties that may help protect against chronic injury and tissue degeneration.
Chemical Properties
| Chemical Name | Thymosin Beta-4 Fragment (TB-500) |
| CAS Number | 77591-33-4 |
| Molecular Formula | C212H350N56O78S |
| Molecular Weight | 4963 g/mol |
| Peptide Class | Regenerative / Healing Peptide |
Potential Benefits of TB-500
- Tissue Repair: Studied for accelerating muscle, tendon, and ligament healing.
- Angiogenesis: May promote new blood vessel formation to support recovery.
- Inflammation Reduction: Early studies show potential for lowering systemic and localized inflammation.
- Performance Recovery: Often researched in athletic injury models for faster return to activity.
- Synergy with BPC-157: Frequently stacked in research with BPC-157 for complementary healing effects.
Clinical Research & Findings
Research into TB-500 has shown promise in enhancing wound healing, cardiac tissue repair, and musculoskeletal recovery. Animal studies highlight its ability to stimulate angiogenesis and speed up the repair of injured tissues. Although human trials remain limited, TB-500 is widely regarded in research settings as one of the leading peptides for injury and recovery studies.
Dosage & Research Protocols
- Research Dose: 2–5 mg per week
- Administration: Typically subcutaneous injection
- Cycle Length: 4–6 weeks for loading, followed by possible maintenance doses
Research protocols often begin with a loading phase of higher doses for several weeks, transitioning into lower maintenance doses to sustain results. TB-500 is frequently studied in combination with BPC-157 for synergistic recovery outcomes.
FAQs
Is TB-500 legal in Canada?
Yes. TB-500 is legal for research use in Canada but is not approved for human consumption.
What makes TB-500 different from BPC-157?
While both are studied for healing, TB-500 focuses more on angiogenesis and systemic recovery, while BPC-157 is often researched for localized tendon, ligament, and gut healing.
Can TB-500 be stacked with BPC-157?
Yes. Research frequently explores TB-500 and BPC-157 together for complementary regenerative and anti-inflammatory effects.
What form does TB-500 come in?
TB-500 is supplied in lyophilized powder form with ≥98% purity for laboratory research purposes.
Disclaimer
For laboratory use only. Not for human or veterinary use.
This peptide is intended strictly for research under controlled laboratory conditions. Buyers are responsible for ensuring legal and ethical compliance with institutional, local, and federal regulations.

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