Semax

What is Semax?

Semax is a synthetic heptapeptide originally developed in Russia as a derivative of the adrenocorticotropic hormone (ACTH 4–7 fragment). Unlike ACTH, it lacks hormonal activity but retains and amplifies neurotropic and cognitive effects. Since its development, Semax has been researched as a nootropic and neuroprotective peptide with potential applications in learning, memory, mood regulation, and recovery from neurological stress.

How Does Semax Work?

Semax influences the central nervous system by modulating neurotransmitter systems, particularly dopamine and serotonin. It also upregulates brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF), both of which play a critical role in neuroplasticity, synaptic growth, and overall brain health. Additionally, Semax has been studied for its antioxidant effects and ability to protect neurons from hypoxic and oxidative stress.

Chemical Properties

Potential Benefits of Semax

• Cognitive Enhancement: Supports learning, memory retention, and focus.
• Neuroprotection: May protect neurons from oxidative and hypoxic stress.
• Mood Regulation: Studied for balancing dopamine and serotonin pathways to reduce anxiety and depression-like symptoms.
• Neuroplasticity: Increases BDNF and NGF expression, supporting long-term brain health.
• Stress Adaptation: Early research suggests improved resilience under cognitive and emotional stress.

Clinical Research & Findings

Semax has been extensively researched in Russia and Eastern Europe for use in cognitive decline, ischemic stroke recovery, and learning support. Studies indicate improvements in short- and long-term memory, enhanced stress tolerance, and neuroprotection following hypoxia or toxic stress. Although global clinical trials are limited, the peptide is increasingly recognized in nootropic research circles for its unique ability to enhance cognition and protect brain function simultaneously.

Dosage & Research Protocols

• Research Dose: 200–600 mcg daily
• Administration: Intranasal spray is the most common route
• Cycle Length: 4–8 weeks

Research protocols often vary depending on the study goals. Lower doses are typically studied for cognitive enhancement, while higher doses are used in neuroprotective research models.

FAQs

Is Semax legal in Canada?

Yes. Semax is legal for research use in Canada but is not approved for human consumption.

What are the main research applications of Semax?

Research focuses on nootropic benefits, neuroprotection, mood stabilization, and stress resilience.

How is Semax administered?

Semax is most often studied as an intranasal spray for rapid absorption.

How does Semax differ from Selank?

While both are Russian-developed nootropic peptides, Semax is primarily studied for cognitive enhancement and neuroprotection, while Selank focuses more on anxiolytic and mood-stabilizing effects.

Disclaimer

For laboratory use only. Not for human or veterinary use.

This peptide is intended strictly for research under controlled laboratory conditions. Buyers are responsible for ensuring legal and ethical compliance with institutional, local, and federal regulations.