MOTS-c

What is MOTS-c?

MOTS-c is a peptide encoded by mitochondrial DNA and is part of a class known as mitochondrial-derived peptides (MDPs). Discovered in 2015, MOTS-c plays a role in regulating metabolism and cellular energy production. It has gained attention in research for its potential to influence glucose utilization, fat metabolism, and physical performance.

How Does MOTS-c Work?

MOTS-c influences key metabolic pathways by activating AMPK (AMP-activated protein kinase), a regulator of energy balance. By enhancing glucose uptake and promoting fatty acid oxidation, MOTS-c supports improved energy efficiency and endurance in research subjects. This mitochondrial peptide is also being investigated for its potential in managing obesity, insulin resistance, and age-related metabolic decline.

Chemical Properties

Potential Benefits of MOTS-c

• Metabolic Health: Supports glucose regulation and insulin sensitivity.
• Weight Management: Encourages fat oxidation and energy balance.
• Enhanced Endurance: Improves exercise performance in preclinical studies.
• Anti-Aging Research: Investigated for its role in mitigating age-related metabolic decline.

Clinical Research & Findings

Early studies suggest MOTS-c can mimic exercise-like effects by activating AMPK and regulating mitochondrial function. Animal research has shown improved glucose tolerance and resistance to diet-induced obesity. Human trials are limited but emerging, with preliminary data pointing to its potential for metabolic and longevity-focused applications.

Dosage & Research Protocols

• Research Dose: 5–10 mg subcutaneous injection
• Frequency: 2–3 times per week
• Cycle Length: Typically 4–8 weeks

As with other peptides, dosing strategies vary depending on research design. Monitoring metabolic markers is recommended throughout study protocols.

FAQs

Is MOTS-c legal in Canada?

Yes. MOTS-c is legal for research use in Canada but is not approved for human consumption.

What makes MOTS-c different from other peptides?

Unlike traditional peptides, MOTS-c is encoded by mitochondrial DNA and directly influences cellular energy regulation.

What are the main research goals for MOTS-c?

Studies focus on metabolic regulation, obesity, insulin resistance, endurance, and anti-aging applications.

What form does MOTS-c come in?

It is provided in lyophilized powder form with ≥98% purity for laboratory research use.

Disclaimer

For laboratory use only. Not for human or veterinary use.

This peptide is intended strictly for research under controlled laboratory conditions. Buyers are responsible for ensuring legal and ethical compliance with institutional, local, and federal regulations.